Erythropoietin (EPO) 3000iu 5boxes (5pieces)



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Erythropoietin (EPO) 3000iu
Erythropoietin (EPO): A hormone produced by the kidney that promotes
the formation of red blood cells in the bone marrow. EPO is a
glycoprotein (a protein with a sugar attached to it). Human EPO has a
molecular weight of 34,000.

The kidney cells that make EPO are specialized and are sensitive to
low oxygen levels in the blood. These cells release EPO when the
oxygen level is low in the kidney. EPO then stimulates the bone marrow
to produce more red cells and thereby increase the oxygen-carrying
capacity of the blood.

EPO is the prime regulator of red blood cell production. Its major
functions are to promote the differentiation and development of red
blood cells and to initiate the production of hemoglobin, the molecule
within red cells that transports oxygen.

The EPO gene has been found on human chromosome 7 (in band 7q21). EPO
is produced not only in the kidney but also, to a lesser extent, in
the liver. Different DNA sequences flanking the EPO gene act to
control kidney versus liver production of EPO.

The measurement of EPO in the blood is useful in the study of bone
marrow disorders and kidney disease. Normal levels of EPO are 0 to 19
mU/ml (milliunits per milliliter). Elevated levels of EPO can be seen
in polycythemia, a disorder in which there is an excess of red blood
cells. Lower than normal levels of EPO are seen in chronic renal
failure.

Using recombinant DNA technology, EPO has been synthetically produced
for use in persons with certain types of anemia -- such as anemia due
to kidney failure, anemia secondary to AZT treatment of AIDS , and
anemia associated with cancer.

EPO has been much misused as a performance-enhancing drug in endurance
athletes including some cyclists (in the Tour de France),
long-distance runners, speed skaters, and Nordic (cross-country)
skiers. When misused in such situations, EPO is thought to be
especially dangerous (perhaps because dehydration can further increase
the viscosity of the blood, increasing the risk for heart attacks and
strokes. EPO has been banned by the Tour de France, the Olympics, and
other sports organizations.

  • Model: Erythropoietin (EPO) 3000iu 6box
  • 19989 Units in Stock


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This product was added to our catalog on Tuesday 17 March, 2009.


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